Functional Cell Types in Taste Buds Have Distinct Longevities

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Functional Cell Types in Taste Buds Have Distinct Longevities

Taste buds are clusters of polarized sensory cells embedded in stratified oral epithelium. In adult mammals, taste buds turn over continuously and are replenished through the birth of new cells in the basal layer of the surrounding non-sensory epithelium. The half-life of cells in mammalian taste buds has been estimated as 8-12 days on average. Yet, earlier studies did not address whether the n...

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Cell types and lineages in taste buds.

Taste buds are the sensory endorgans for gustation. In mammals, taste buds comprise a collection of ~50–100 elongate epithelial cells and a small number of proliferative basal cells. Ultrastructural studies reveal three distinct anatomical types of elongate taste cells within each taste bud: Type I, Type II and Type III, first defined by Murray based on his studies of rabbit foliate taste buds ...

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Identification of electrophysiologically distinct cell subpopulations in Necturus taste buds

We used the patch clamp technique to record from taste cells in thin transverse slices of lingual epithelium from Necturus maculosus. In this preparation, the epithelial polarity and the cellular organization of the taste buds, as well as the interrelationships among cells within the taste bud, were preserved. Whole-cell recording, combined with cell identification using Lucifer yellow, allowed...

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Filiform papillae do not have taste buds.

1 Professor Assistente (Palestrante). 2 Mestrado (Assistente). 3 Professor (Palestrante). Endereço para correspondência: Mehmet Fatih Sönmez. Department of Histology and Embryology, Faculty of Medicine, Erciyes University, 38039 Kayseri, Turkey. Tel: (+90) 352 4374901 x 23356. Fax: (+90) 352 4375285 Este artigo foi submetido no SGP (Sistema de Gestão de Publicações) da BJORL em 17 de dezembro d...

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Taste buds have a cyclic nucleotide-activated channel, CNGgust.

Cyclic nucleotide-gated (CNG) channels have been characterized as important factors involved in physiological processes including sensory reception for vision and olfaction. The possibility thus exists that a certain CNG channel functions in gustation as well. In the present study, we carried out reverse transcription-polymerase chain reaction and genomic DNA cloning and characterized a CNG cha...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2013

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0053399